Targeted HD Wipe Sampling with USP <800> Compliance – Safer Surfaces, Smarter Monitoring!

USP <800> states the following: Environmental wipe sampling for HD surface residue should be performed routinely (e.g., initially as a benchmark and at least every 6 months, or more often as needed, to verify containment).

SOME RECOMMENDED AREAS to be sampled:

  • Front grille within the C-PEC
  • Cart beside the C-PEC
  • Passthrough
  • Floor in front of the C-PEC
  • Armrest of a patient treatment chair

HD Wipe Sampling

Groups of drugs Limit of detection
(ng per paper)
Group 1F
fluorouracil
2
Group 1M
methotrexate
1
Group 2
cytarabine
dacarbazine
DOXOrubicin
epirubicin
gemcitabine
melphalan
2.5
0.5
10
10
0.5
1
Group 3
cyclophosphamide
DOCEtaxel
etoposide
ifosfamide
irinotecan
methotrexate
PACLitaxel
PEMEtrexed
topotecan
vinBLAStine
vinCRIstine
0.5
30
2
0.5
2
1
10
2
1
5
5
Group 4
Platins: (CISplatin, oxaliplatin, CARBOplatin)
0.5
Group 5
All hazardous drugs in groups 1 to 4
0.5